June 20, 2018
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Top stories in endocrinology: formulation of levothyroxine therapy may influence adherence, autoimmunity may play role in PCOS etiology

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Among the top stories in endocrinology is an analysis of claims data showing patients with hypothyroidism were more likely to adhere to treatment at 1 year when prescribed specific formulations of levothyroxine therapy. Autoimmunity may play a role in polycystic ovary syndrome as findings showed that Indian women with the condition were more likely to test positive for serum antinuclear antibody vs. healthy controls. Other top stories include CMS stating that Medicare will soon cover smartphone apps used in conjunction with approved continuous glucose monitors for people with diabetes, lipid deposits in the liver and skeletal muscles of postmenopausal women may be connected to an increased risk of insulin resistance, and rates of initiation and intensification of diabetes therapies have increased despite some patients receiving inadequate medication or no prescribed antidiabetes agents.

In hypothyroidism, formulation of levothyroxine therapy may influence adherence rates

Patients with hypothyroidism prescribed levothyroxine therapy were more likely to adhere to treatment at 1 year when prescribed specific formulations of the drug, according to an analysis of claims data published in Current Medical Research and Opinion. Read More.

Autoimmunity may play role in PCOS etiology

Indian women with polycystic ovary syndrome were nearly eight times more likely to test positive for serum antinuclear antibody vs. healthy controls, suggesting that autoimmunity may play a role in the condition, according to findings published in Gynecological Endocrinology. Read More.

CMS: Medicare to cover smartphone apps used with CGM

Medicare will soon cover smartphone apps used in conjunction with approved continuous glucose monitors for people with diabetes, according to a statement released by CMS. Read More.

Lipid deposition in liver, skeletal muscle may induce postmenopausal insulin resistance

Postmenopausal women have increased lipid deposits in the liver and skeletal muscle vs. premenopausal women that coincide with an increase in visceral fat mass, suggesting a mechanistic link between the changes in fat depots and increased incidence of insulin resistance seen after menopause, study data show. Read More.

Diabetes therapy initiation, intensification rates growing

About a third of patients with uncontrolled diabetes have no prescribed antidiabetes medications and about 15% are prescribed inadequate medications; however, rates of initiation and intensification of diabetes therapies increased between 2008 and 2015, according to a study published in Diabetes Care. Read More.

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