This article is more than 5 years old. Information may no longer be current.

Top stories in endocrinology: FDA clears insulin pump system, oral macimorelin safe test for growth hormone deficiency

Among the top stories in endocrinology is an announcement that the FDA has granted 510(k) clearance for the Omnipod DASH Insulin Management System, a tubeless insulin pump system that wirelessly connects to a bolus calculator and two smartphone apps. Another top story includes an open-label, two-way crossover trial showing that adults with suspected growth hormone deficiency can be safely and effectively diagnosed with the oral ghrelin agonist macimorelin.

Also of interest to Healio readers were findings that alternative surrogate measurements of central body shape and fat accumulation are not superior indicators of cardiometabolic risk compared to the currently recommended measurements of waist circumference and BMI.

Other top stories included a study that found that women who maintain sufficient vitamin D concentrations before conception could achieve higher live birth pregnancy rates and reduced risk for pregnancy loss, and a statement from the Endocrine Society that declared that the European Union’s criteria for regulating endocrine-disrupting chemicals in pesticides and biocides do not go far enough to protect public health.

FDA clears insulin management system

The FDA granted 510(k) clearance for the Omnipod DASH Insulin Management System, a tubeless insulin pump system that wirelessly connects to a bolus calculator and two smartphone apps for diabetes management, Insulet announced in a press release. Read More.

Oral macimorelin safe diagnostic test for adult growth hormone deficiency

Among adults with suspected growth hormone deficiency, the oral ghrelin agonist macimorelin is a safe and effective alternative growth hormone stimulation agent vs. the more invasive and potentially risky insulin tolerance test, according to findings from an open-label, two-way crossover trial. Read More.

Alternatives to waist circumference, BMI ‘weak’ predictors of cardiometabolic risk

Alternative surrogate measurements of central body shape and fat accumulation are not superior indicators of cardiometabolic risk when compared against the currently recommended measurements of waist circumference and BMI, according to findings published in Clinical Nutrition. Read More.

Preconception vitamin D level may affect pregnancy outcome

Women who maintain sufficient vitamin D concentrations before conception may achieve higher live birth pregnancy rates while also experiencing a reduced risk for pregnancy loss, according to a study published in The Lancet Diabetes & Endocrinology. Read More.

Endocrine Society: New European criteria for endocrine-disrupting chemicals fall short

The European Union’s criteria for regulating endocrine-disrupting chemicals in pesticides and biocides do not go far enough to protect public health, according to a statement issued this week by the Endocrine Society. Read More.