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Top stories in endocrinology: Anxiety levels may predict fracture risk, improved diagnosis of benign thyroid nodules

Among the top stories in endocrinology is a report confirming postmenopausal women with osteoporosis with high levels of anxiety are at an increased risk for bone fracture. A study found that Danish women with polycystic ovary syndrome are more likely to develop cardiovascular disease or hypertension over 11 years. Other stories include a study that found that consuming more seafood may influence the time it takes for a couple to report pregnancy, a new genomic sequencing classifier improved identification ofthyroid nodules with indeterminate cytology as benign, and women with overweight or obesity during the early stages of pregnancy have a greater risk of giving birth to children with neurodevelopmental delays.

Anxiety levels may predict fracture risk in postmenopausal women

Among postmenopausal women with osteoporosis, higher anxiety levels increased risk for bone fracture, according to findings published in Menopause. Read More.

Risk for CVD nearly double in women with PCOS

Danish women with polycystic ovary syndrome are more likely to develop cardiovascular disease or hypertension over 11 years vs. women without PCOS; the risk was further increased by the presence of obesity, diabetes, infertility and previous use of contraception, according to study findings presented at the European Congress of Endocrinology annual meeting. Read More.

Seafood intake may influence time to pregnancy among couples trying to conceive

Couples in which both partners consume at least two servings of seafood per week are more likely to report pregnancy within 12 months and a greater frequency of sexual intercourse vs. couples consuming seafood less than once per menstrual cycle, according to findings published in the Journal of Clinical Endocrinology & Metabolism. Read More.

Novel genomic sequence classifier improves detection of benign thyroid nodules

A new genomic sequencing classifier accurately classified more thyroid nodules with indeterminate cytology as benign vs. its predecessor, the gene expression classifier, potentially eliminating unnecessary surgery for some patients, according to findings from a masked validation study published in JAMA Surgery. Read More.

Early pregnancy obesity, overweight linked to neurodevelopmental delay in offspring

Children born to women with overweight or obesity during the early stages of pregnancy have a greater risk for neurodevelopmental delays than those born to women with normal weight, according to results from the PREDO study published in the International Journal of Obesity. Read More.