May 07, 2018
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Prostate, lung cancer most common cancers in HIV patients by 2030

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Among aging individuals with HIV, prostate and lung cancers are expected to emerge as the most common cancer types by 2030, according to new research published in Annals of Internal Medicine.

“Persons living with HIV have an elevated risk for certain types of cancer. With modern antiretroviral therapy, persons living with HIV are aging and cancer rates are changing,” Meredith S. Shiels, PhD, MHS, from the National Cancer Institute, and colleagues wrote.

Shiels and colleagues studied data from HIV and cancer registries to estimate the incidence rates of cancer and future burden in adults with HIV in the United States by 2030. Cancer burden was defined as incident cancer diagnoses.

The researchers projected that in the United States, the number of persons living with HIV aged 65 years or older will rise 21.4% by 2030, an increase of 12.9% from 2010.

Age-specific rates of colon cancer in patients aged 65 years or older, as well as Kaposi’s sarcoma, non-Hodgkin’s lymphoma, cervical cancer, lung cancer, Hodgkin’s lymphoma and other cancer types combined are estimated to decline through 2030.

Conversely, rates of prostate cancer are expected to rise and it is estimated to be the most common cancer type among persons living with HIV in 2030, along with lung cancer.

The total cancer burden is projected to decline in persons living with HIV to 6,690 cases by 2030, a decrease of 1,460 cases from 2010.

The researchers note that non-AIDS-defining cancers will continue to be a concern.

“Cancer will remain an important comorbid condition, and expanded access to HIV therapies and cancer prevention, screening and treatment is needed,” Shiels and colleagues concluded. – by Alaina Tedesco

Disclosure: Please see study for the authors’ relevant financial disclosures.