Accommodation increases throughout day with low-dose atropine
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NEW ORLEANS — Objectively measured accommodative amplitude increased throughout the day in children using low-dose atropine for myopia management, according a study presented at Academy ’23.
“Typically, subjective amplitude is evaluated by push-up test,” Kaylin Maxwell, BS, said at an academy-sponsored press conference. “This study looked at whether objective accommodative ability changes throughout the day.”
Maxwell, a third-year student at The Ohio State University College of Optometry, and colleagues measured objective amplitudes of accommodation in 10 children between the ages of 7 and 10 years who were using 0.05% atropine drops in the evening to slow progression of myopia.
Measurements were taken with a Grand Seiko autorefractor and monocular estimated method (MEM) retinoscopy at morning, midday and afternoon, she said.
“When we looked at accommodative amplitude throughout the day we saw a significant change in morning amplitude vs. afternoon and midday vs. afternoon, but not a significant difference between morning and midday,” Maxwell said.
According to the study, the mean accommodative amplitudes were 7.18 ±1.47 D in the morning, 7.19 ±1.57 D at midday and 8.11 ±1.15 D in the afternoon.
“Through this objective measurement we would expect the amplitudes to be 8.5 D for this age range,” Maxwell said. “There was a lot of individual variation among participants.”
The researchers determined there was a significant change in accommodative amplitude throughout the course of the day in children using low-dose atropine.
“We thought about in the future if kids are using atropine and having side effects, maybe we could change the timing of the drops,” Maxwell said. “They could instill them earlier in the evening. Most did it between 9 p.m. and 10 p.m. If they did it earlier in the evening, that would give the side effects a chance to wear off.”
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Maxwell K, et al. Change in ocular accommodation over the day in children using 0.05% low dose atropine. Presented at: Academy; Oct. 11-14, 2023; New Orleans.
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