Loss of sensitivity in central vision associated with reduced quality of life
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Key takeaways:
- Decrease in sensitivity of the inferior nasal point had the strongest relationship with visual-related quality of life.
- Mild decreases in sensitivity led to poorer quality of life.
INDIANAPOLIS — Loss of sensitivity in the central visual field may be associated with lower vision-related quality of life, especially in the inferior nasal point, according to a presentation at Academy 2024.
“In cases of early glaucoma, we’re figuring out if the central-most points on that 24-2 visual field have any relationship to vision-related quality of life,” Anupam Laul, OD, associate clinical professor at SUNY College of Optometry, said.
To do this, Laul and colleagues conducted a cross-sectional study of 83 patients (mean age, 72.6 years; 93% men) with primary open-angle glaucoma at the Veterans Affairs Medical Center in Albuquerque, New Mexico. All patients completed two vision-related quality of life surveys and underwent visual field sensitivity measurements of the central four 24-2 visual field points in each eye.
According to Laul, 39 patients had mild visual field loss in their worse eye but no visual field loss in their better eye, and 21 had mild visual field loss in both eyes. Median cumulative quality of life scores were 92.1 on the NEI-VFQ-25 and 91.7 on the GQL-15.
The researchers found that worse mean deviation in the poorer eye correlated with poorer quality of life. Decrease in sensitivity of the inferior nasal point had the strongest relationship with visual-related quality of life, and even small amounts of sensitivity loss were associated with decreasing quality of life.
“Even mild decreases in sensitivity in that inferior point on that 24-2 led to potentially worse vision-related quality of life,” Laul said.
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Laul A, et al. Central-most 24-2 point visual field sensitivity and quality of life in early glaucoma. Presented at: Academy 2024; Nov. 6-9, 2024; Indianapolis.
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