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Retina/Vitreous News

Phase 3 COAST trial of wet AMD combination therapy misses primary endpoint
The phase 3 COAST trial investigating 2 mg sozinibercept for the treatment of wet age-related macular degeneration in combination with 2 mg aflibercept did not meet its primary endpoint, according to a press release from Opthea.
Retinal re-detachment risk significant in cataract patients who underwent vitrectomy

ATHENS, Greece — Retinal re-detachment following cataract extraction remains significant in patients who have previously undergone pars plana vitrectomy for retinal detachment, according to a study.
FDA approves expanded label for Iluvien

The FDA approved an expanded label for Iluvien, which is now indicated for the treatment of chronic noninfectious uveitis affecting the posterior segment of the eye, according to a press release from ANI Pharmaceuticals.
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Q&A: Altris AI launches AI-powered optic disc analysis

Altris AI, which offers OCT analysis for retinal diseases, is now expanding to glaucoma detection.
FDA grants fast track designation to X-linked retinoschisis treatment

The FDA granted fast track designation to ATSN-201 for the treatment of X-linked retinoschisis, according to a press release from Atsena Therapeutics.
FDA approves Encelto for macular telangiectasia type 2

The FDA approved Encelto, an encapsulated cell therapy, for the treatment of macular telangiectasia type 2, according to a press release from Neurotech Pharmaceuticals.
Older patients with DME have weaker response to anti-VEGF treatment

Older patients with diabetic macular edema have a weaker response to anti-VEGF treatment, according to a presentation at Angiogenesis, Exudation, and Degeneration 2025.
GA lesion location plays role in vision-related quality of life

Geographic atrophy lesion location may be a critical factor in vision-related quality of life, according to a presentation at Angiogenesis, Exudation, and Degeneration 2025.
VIDEO: Systemic therapies may run risk of retinal toxicity
ORLANDO — In this Healio Video Perspective from Telling It Like It Is, Jaclyn L. Kovach, MD, FASRS, overviews systemic therapies and retinal toxicity.
Advances in AI stand to greatly improve diagnosis, treatment of AMD, but hurdles remain

Although AI shows significant promise in diagnosing and managing age-related macular degeneration, its efficacy is reduced by bias, data quality and limited generalizability, according to a review published in BMJ Open Ophthalmology.
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