Oncology News

CHICAGO — Adjuvant FOLFIRINOX chemotherapy improved OS and PFS compared with gemcitabine among patients with surgically removed nonmetastatic pancreatic ductal adenocarcinoma, according to data from the phase 3 PRODIGE 24/CCTG PA.6 trial presented at ASCO Annual Meeting.

Fibrolamellar hepatocellular carcinoma, a rare childhood liver cancer, metastasized to the brain, prompting researchers to recommend surveillance neuroimaging for patients with advanced disease, according to published findings.

Exelixis announced that the FDA accepted a supplemental new drug application for Cabometyx tablets as a treatment for patients with previously treated advanced hepatocellular carcinoma, according to a press release.

Patients with hepatitis B-related decompensated cirrhosis who achieved virologic response after treatment with either Baraclude or Epivir had significantly improved long-term and transplant-free survival, according to results of a 10-year observational study.

Overweight and obesity appeared associated with an increased risk for 12 cancer types, according to World Cancer Research Fund’s new report.

Results of two phase 3 trials showed that Doptelet significantly reduced the need for platelet transfusions or rescue procedures for bleeding compared with placebo in patients with thrombocytopenia and chronic liver disease who underwent a scheduled procedure.

The FDA approved avatrombopag to treat low blood platelet count among adults with chronic liver disease who are scheduled to undergo a medical or dental procedure.

Residents of Japan with higher concentrations of vitamin D were less likely to develop cancer than those with lower levels, according to a cohort study recently published in The BMJ.

Diabetes and high blood glucose levels in individuals without a diabetes diagnosis correlated with increased risks for liver cancer and major chronic liver diseases, according to a large prospective study of Chinese adults.

Radiation segmentectomy conferred comparable response rates, tumor control and survival outcomes as curative-intent treatments among certain patients with early-stage hepatocellular carcinoma, according to findings published in Radiology.