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Autoimmune/Cholestatic/Biliary Diseases News
VIDEO: Preclinical research investigates role of Claudin-1 in cholangiocarcinoma
BOSTON — Healio spoke with James L. Boyer, MD, FACEP, about research assessing the role of Claudin-1 in cholangiocarcinoma, which was presented at The Liver Meeting.
Patients with MASLD lost less weight after bariatric surgery, study finds
BOSTON — Patients with metabolic dysfunction-associated steatotic liver disease who underwent bariatric surgery lost less weight over 5 years than those without MASLD, according to research presented at The Liver Meeting.
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Elafibranor achieves response, improves pruritus symptoms in primary biliary cholangitis
BOSTON — After 52 weeks, elafibranor achieved biochemical response and improved symptoms of pruritus in patients with primary biliary cholangitis, according to late-breaking data presented at The Liver Meeting.
VIDEO: Primary biliary cholangitis treatments poised to be clinically ‘impactful’
BOSTON — Healio spoke with James L. Boyer, MD, about phase 3 findings from the RESPONSE trial and the ELATIVE trial and presented at The Liver Meeting.
FDA grants fast track status to monoclonal antibody for primary sclerosing cholangitis
The FDA has granted fast track designation to Chemomab Therapeutics’ anti-CCL24 monoclonal antibody, CM-101, for the treatment of adults with primary sclerosing cholangitis, according to a manufacturer release.
VIDEO: Treatment with Livmarli yields ‘broad base effects’ across range of PFIC types
BOSTON — In a Healio video exclusive, Pam Vig, PhD, reports late-breaking data that show Livmarli improved liver health and maintained symptom response over 2 years among pediatric patients with progressive familial cholestasis.
Robotic-assisted cholecystectomy linked to higher rates of bile duct injury, complications
Although the use of robotic-assisted cholecystectomy increased 37-fold from 2010 to 2019, the procedure was associated with significantly higher rates of bile duct injury compared with laparoscopic cholecystectomy, according to research.
‘Ask me about PBC’ campaign calls on patients to speak up for rare liver disease
International Primary Biliary Cholangitis Day, celebrated on September 10, aspires to raise awareness of the challenges that patients with this rare liver disease face and how their stories can help advance diagnosis, treatment and care.
FDA grants orphan drug designation to inhaled therapy for alpha-1 antitrypsin deficiency
The FDA granted orphan drug designation for KB408 for the treatment of alpha-1 antitrypsin deficiency, according to a press release from Krystal Biotech.
RESPONSE topline data: Seladelpar normalized alkaline phosphatase, reduced pruritus in PBC
Seladelpar reduced serum alkaline phosphatase and bilirubin at 12 months in more than 60% of patients with primary biliary cholangitis compared with 20% of placebo-treated patients, according to manufacturer, CymaBay Therapeutics.
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Headline News
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December 03, 20243 min read -
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Headline News
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