Top news of July: Anaphylaxis guidelines, epinephrine, FDA applications, more
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Healio has compiled July’s most-read news in asthma and allergy.
Top stories included guidelines in identifying anaphylaxis as well as asthma treatment in pregnant patients, career advice from women allergists, the impact of childhood illnesses on asthma and more.
Modified guidelines identify anaphylaxis in more infants, young children
Modified criteria that incorporated symptoms specific to infants and young children increased identification of anaphylaxis in these age groups, Michael Pistiner, MD, MMSc, director of food allergy advocacy, education and prevention, Mass General for Children, explained. Read more.
Epinephrine nasal spray recommended for approval in European Union
An epinephrine nasal spray is closer to approval in Europe, according to a press release from ARS Pharmaceuticals. The recommendation was based on data from more than 700 study participants. Richard Lowenthal, cofounder, president and CEO of ARS Pharmaceuticals, and Sung Poblete, PhD, RN, CEO of Food Allergy Research & Education, commented on the action. Read more.
Safety profiles similar for benralizumab, mepolizumab in severe eosinophilic asthma
Mepolizumab and benralizumab had similar safety profiles for patients with severe eosinophilic asthma despite their different mechanisms, according to a study published in The Journal of Allergy and Clinical Immunology: In Practice. Andrew Menzies-Gow, MD, global medical head, respiratory biologics, AstraZeneca, and Vickram Tejwani, MD, shared their thoughts on the results. Read more.
KalVista Pharmaceuticals submits FDA application for sebetralstat
KalVista Pharmaceuticals submitted a new drug application to the FDA for the approval of sebetralstat for patients aged 12 years and older with hereditary angioedema, according to a company press release. Read more.
Asthma treatment guidelines aim to provide 'best possible care' for pregnant patients
Pregnant women should continue their medications if their asthma is well controlled, although more research is needed about safety of newer drugs, such as biologics, for pregnant patients. Sarah A. Bendien, MD, respiratory physician at Haga Teaching Hospital in The Hague, Netherlands, calls for attention to preconception health. Jennifer Namazy, MD, FAAAAI, and Vanessa Murphy, PhD, commented on the topic. Read more.
Childhood illnesses associated with risks for chronic rhinosinusitis in middle age
Children with asthma, frequent head colds and tonsilitis at age 7 years face greater risks for chronic rhinosinusitis in middle age and may benefit from closer monitoring and proactive management, according to a study published in Allergy. Jennifer Perret, MBBS, FRACP, PhD, physician-trained respiratory and sleep epidemiologist at the allergy and lung health unit, Centre for Epidemiology and Biostatistics, Melbourne School of Population and Global Health, explained more. Read more.
Most caregivers of children with food allergies go online at least weekly for information
More patients are using online platforms to obtain information on food allergies, trusting professional organizations and allergists the most, Aikaterini (Katherine) Anagnostou, MD (Hons), MSc, PhD, professor of pediatrics, allergy and immunology division at the Baylor College of Medicine, told Healio. Tori Martel, MPH, of Allergy & Asthma Network, also shared her thoughts. Read more.
‘Follow the science and follow your gut’ to make a change in medicine
Emma Guttman-Yassky MD, PhD, Waldman Professor of Dermatology and Immunology and System Chair of the Kimberly and Eric J. Waldman Department of Dermatology at the Icahn School of Medicine at Mount Sinai, is considered one of the world’s leading experts in inflammatory skin diseases, according to a press release from Mount Sinai. She is the recipient of this year’s Paul Ehrlich Award for Experimental Research and spoke to Healio about the importance of mentorship and sticking to your beliefs in our Women in Allergy series. Read more.
Physician recommends creative thinking to achieve career ambitions, manage your practice
Vivian Hernandez-Trujillo, MD, found a way to run her own practice and continue working with fellows. She advises young allergists to be creative when figuring out how to achieve work-life balance. “You are the owner of your happiness,” Hernandez-Trujillo, who also serves as a Healio Women in Allergy Peer Perspective Board Member, said. “If you are not happy, you can make a change. You can do something different.” Read more.
Children achieve remission in eosinophilic esophagitis with dupilumab
There were significant differences in percentages of children with eosinophilic esophagitis who experienced histologic remission with dupilumab compared with placebo, according to Mirna Chehade, MD, MPH, professor of pediatrics and medicine at Icahn School of Medicine at Mount Sinai and founding director of the Mount Sinai Center for Eosinophilic Disorders. Mark Holbreich, MD, and Elizabeth T. Jensen, MPH, PhD, weighed in. Read more.