Anaphylaxis
Sublingual epinephrine outcomes fall between manual injection, autoinjectors
Sublingual delivery of epinephrine achieved pharmacokinetic and pharmacodynamic results that were comparable with manual intramuscular injection and autoinjectors, according to a study published in Annals of Allergy, Asthma & Immunology.
Consensus report defines anaphylaxis, provides clinical support tool
The Global Allergy and Asthma Excellence Network has published a consensus report on anaphylaxis — including an updated definition, overview and clinical support tool — in The Journal of Allergy & Clinical Immunology.
Epinephrine nasal spray yields responses with, without allergic rhinitis
Participants in a clinical trial who used Belhaven Biopharma’s Nasdepi dry powder epinephrine nasal spray experienced positive outcomes regardless of whether they had induced allergic rhinitis, according to a press release.
Epinephrine autoinjector administration diagrams differ from evidence-based best practice
SAN DIEGO — Standing vs. supine or sitting was the position in which an epinephrine autoinjector device was administered in several written and visual examples showing administration, according to a poster presented here.
Parents of children with wheat allergy reveal gaps in knowledge, confidence
SAN DIEGO — When children have a wheat allergy, it can significantly affect the quality of life of their parents, but education and support may mitigate these impacts, according to an abstract presented here.
Sublingual epinephrine film demonstrates potency, durability in real-world conditions
SAN DIEGO — Aquestive Therapeutics’ Anaphylm AQST-109 epinephrine sublingual film demonstrated durability despite testing in extreme temperatures and other environmental conditions, according to a pair of posters presented here.
Asthma, age, cardiovascular disease associated with severe anaphylaxis
SAN DIEGO — About a third of adults with anaphylaxis due to food allergy have visited the ED for their allergy before, with asthma, age and cardiovascular disease associated with severe cases, according to a pair of posters presented here.
University dining halls lack food allergy labeling, access to epinephrine
SAN DIEGO — College students with food allergies may find difficulty in finding ingredient labeling and emergency epinephrine access in dining halls, according to a presentation here.
FDA approves epinephrine nasal spray for children aged as young as 4 years
The FDA has approved neffy 1 mg epinephrine nasal spray for treating anaphylaxis and other type 1 allergic reactions in children aged 4 years and older, according to a press release from ARS Pharma.
Chart review supports expansion of subcutaneous immunotherapy, oral food challenges
SAN DIEGO — A retrospective chart review of patients with allergy who participated in subcutaneous immunotherapy and oral food challenges suggested that these therapies should be expanded, according to a pair of posters presented here.