The Glucocorticoid Toxicity Index with John Stone, MD, MPH

ByAdam J. Brown, MD

Glucocorticoids can do a lot of harm over time. In this episode, John Stone, MD, MPH, walks us through the Glucocorticoid Toxicity Index, a validated tool to measure steroid toxicity over time that we’ll be seeing more of in the future.

Intro :11
Dr. Stone introduction :26
About the GTI 1:13
Professional development opportunities for rheumatologists 2:32
The interview 4:27
What is the GTI, how did it come about and how do you think rheumatologists now and in the future will be utilizing it?5:28
What are the difficulties in measuring steroid toxicities in trials? 10:58
How did you go about putting this instrument together? 13:04
What makes up the GTI? 19:11
Can you explain the Cumulative Worsening Score and the Aggregate Improvement Score? 20:53
Walk us through a patient coming in and being evaluated for the GTI 25:49
What's the future of the GTI in your opinion? 30:32
Do you think the GTI is going to be something that can eventually be used in day-to-day clinical practice? 33:42
Thank you, Dr. John Stone 34:43

John Stone, MD, MPH, is director of clinical rheumatology at Massachusetts General Hospital.

We’d love to hear from you! Send your comments/questions to Dr. Brown at rheuminationspodcast@healio.com. Follow us on Twitter @HRheuminations @AdamJBrownMD @HealioRheum

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Sources/Disclosures

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Disclosures: Stone is one of the experts who developed the Glucocorticoid Toxicity Index.

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The Glucocorticoid Toxicity Index with John Stone, MD, MPH

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