Case 3: Results
Christoph U. Correll, MD, professor of psychiatry at The Zucker School of Medicine at Hofstra/Northwell and professor and chair of the department of child and adolescent psychiatry at Charité University Medicine in Berlin, Germany, discusses the results of the third case.
Editor’s note: The following is an automatically generated transcript of the above video.
"Let's look at that in more detail. So the discontinuation of aripiprazole and time-limited treatment with vitamin E until week 12 resulted definitely in an improved TD symptomatology, and ultimately even in remission of her symptoms, that had also been only of recent onset and not more expressed than mildly. Let's review her ratings at baseline. She had facial expression at minimal, barely noticeable, and two twos, two mild movements, one of the tongue and one of the fingers, interfering with her speech, and also with her other fine motor skills.
Vitamin E 400 international units were started. At four weeks, that was increased to 800, and at that time she already had an improvement because she was also off the aripiprazole. Facial expression was now zero. Tongue had only one, and the fingers were still at a two. At eight weeks, this had already fortunately reduced to only minimal movements, both in the tongue and the fingers. There was nothing on the facial expression that came up again. And as of 12 weeks there was actually no further movement. She was very, very lucky. And in this case, that was then sustained at week 24."