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Substance Use Disorders News
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People who need hospital-based care for cannabis use disorder at a greater risk for death
Individuals who required hospital-based care for cannabis use disorder faced nearly three times the risk for premature death, results from a cohort analysis published in JAMA Network Open showed.
Few receive effective treatment for mental health, substance use
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Less than 7% of individuals with mental health or substance use disorders receive effective treatment worldwide, according to a cross-sectional analysis published in JAMA Psychiatry.
Yearly overdose deaths equal an ‘entire Vietnam war’ despite receding pandemic-era spike
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The rates of fatal drug overdoses stayed higher than expected in most states from 2020 to 2023 compared with trajectories before 2020, a cross-sectional analysis in JAMA Network Open showed.
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Cannabis legalization linked to rise in related schizophrenia cases in Canada
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The incidence of cannabis use disorder associated with schizophrenia almost tripled among Canadian teenagers and adults after cannabis legalization, according to a study published in JAMA Network Open.
Addiction, depression, cognition: How GLP-1s may benefit the brain
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As the body of research expands on the potential of glucagon-like peptide-1 receptor agonists to address various health issues, recent data suggest they may improve brain health.
Barriers persist to accessing substance use disorder treatment despite greater need
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Although the prevalence of substance use disorder increased during the COVID-19 pandemic, the receipt of treatment declined before rebounding, according to a research letter published in JAMA Network Open.
Researchers stress need for clear, consistent standards in FDA review of psychiatric drugs
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The FDA approved 16 psychiatric drugs over the last decade, most of which shared similar mechanisms of action with previously developed drugs, according to data in a research latter published in JAMA Network Open.
Use of genetic variants to predict opioid use disorder risk may lead to inaccurate results
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Candidate genetic variants included in a genetic risk algorithm may not meet standards of reasonable clinical efficacy in identifying opioid use disorder risk, according to a study published in JAMA Network Open.
Mindfulness treatment program reduces cravings in those with opioid addiction
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An online-based mindfulness treatment program significantly reduced opioid craving among participants with opioid use disorder results from a randomized clinical trial published in JAMA Network Open showed.
Low-dose buprenorphine initiation shows limited success among fentanyl users with OUD
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Low-dose initiation of buprenorphine in an outpatient setting showed low rates of success among a cohort of adults with opioid use disorder who self-reported daily fentanyl use, according to a study published in JAMA Network Open.
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