Bioinductive collagen implant may yield positive outcomes for rotator cuff augmentation
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Key takeaways:
- A bioinductive collagen implant may yield positive outcomes for patients with rotator cuff tears.
- Research shows the implant was associated with significant clinical, functional and cost improvements.
For patients with rotator cuff tears, augmentation with a bioinductive collagen implant may yield positive outcomes with low rates of retears and improved tendon thickness, according to published results.
Eoghan T. Hurley, MB, MCh, PhD, and colleagues from the department of orthopedic surgery at Duke University used the MEDLINE, Embase and Cochrane Library databases to perform a systematic review of 21 studies that assessed the efficacy of bioinductive collagen implants for 1,531 patients with rotator cuff tears.
Among seven studies that reported American Shoulder and Elbow Surgeons scores, Hurley and colleagues found a bioinductive collagen implant yielded statistically significant improvements in preoperative to postoperative ASES scores for patients with full-thickness and partial-thickness tears.
Hurley and colleagues found ranges for percent increases in tendon thickness ranged from 13% to 44% for patients with full-thickness tears and 14% to 60% for patients with partial-thickness tears. They found retear rates ranged from 0% to 9% for patients with full-thickness tears and 0% to 18% for patients with partial-thickness tears.
Among two studies that reported on costs, Hurley and colleagues found augmentation with a bioinductive collagen implant was associated with cost savings between $5,338 and $13,061 for every healed rotator cuff tendon.
Hurley and colleagues noted the increased incidence of adhesive capsulitis, which was reported in several studies, may warrant further research.
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