Multimorbidity, poor self-rated health may lead to fracture, mortality in trauma patients
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Key takeaways:
- Multiple comorbidities and poor self-rated health were associated with increased risk of subsequent fracture and mortality.
- Results were analyzed from 25,280 patients with incident fractures.
According to published results, patients with incident fractures who have multimorbidity and poor self-rated health may be at increased risk for subsequent fractures and mortality.
Researchers performed a prospective cohort study of 25,280 patients who sustained incident fractures between July 2005 and December 2009. According to the study, patients were followed until subsequent fracture, death or conclusion of the study in April 2017. Median follow-up was 2.8 years.
Researchers analyzed any associations between Charlson Comorbidity Index (CCI) scores and self-rated health with risk of subsequent fracture and mortality.
Among all patients, 2,540 women (16%) and 1,135 men (12%) sustained a subsequent fracture, while 2,281 women (14%) and 2,140 men (24%) died during the study period without a subsequent fracture.
Researchers found patients who had a CCI score of 2 to 3 had an increased risk for subsequent fracture (women: HR = 1.16; men: HR = 1.25) and mortality (women: HR = 2.19; men: HR = 1.89) compared with patients who had a CCI score of less than 2. In addition, researchers found patients who had a CCI score of 4 or more had the highest risk for subsequent fracture (women: HR = 1.33; men: HR = 1.48) and mortality (women: HR = 4.48; men: HR = 3.82) among all patients.
Researchers noted patients with poor self-rated health and quality of life were significantly associated with increased risks for subsequent fracture and mortality.
“The findings suggest the need to develop a practical framework for treating patients with multiple health conditions who sustain a fracture, who are usually underdiagnosed and undertreated,” the researchers wrote in the study.
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