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April 18, 2024
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Regardless of oral contraceptive use, women had fewer musculotendinous injuries vs. men

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Key takeaways:

  • Women who used oral contraceptives had the lowest rates of musculotendinous injuries vs. women who did not use oral contraceptives and men.
  • Overall, women had fewer injuries compared with men.

Women, regardless of whether they use oral contraceptives, may be less likely to develop musculotendinous injuries compared with men, according to published results.

Researchers compared incidences of orthopedic musculotendinous injuries (MTI) between 42,267 women using oral contraceptives, 42,267 women not using oral contraceptives and 42,267 men. All cohorts were matched based on age and BMI.

Birth control pills
Women who used oral contraceptives had the lowest rates of musculotendinous injuries vs. women who did not use oral contraceptives and men. Image: Adobe Stock

Researchers found 231 women (0.55%) using oral contraceptives, 1,078 women (2.55%) not using oral contraceptives and 1,476 men (3.49%) developed an MTI.

After controlling for potential covariates, researchers noted the differences in incidences of MTI for both women who did and those who did not use oral contraceptives were statistically significant compared with men. They concluded women who used oral contraceptives (adjusted OR = 0.15) and women who did not use oral contraceptives (aOR = 0.72) were at a decreased risk for MTI compared with men.

Researchers noted a significantly decreased incidence of MTI in women who used oral contraceptives compared with women who did not.

“The sex hormone milieu (lower concentrations of endogenous [estradiol] E2 and progesterone through exposure to exogenous [ethinyl estradiol] EE and progestin) may be associated with a smaller percentage of MTI compared with overall injuries,” the researchers wrote in the study.

“This study adds to the emerging body of literature on musculoskeletal injuries that are associated with sex hormones but more specifically provides data on MTI, which has not been rigorously investigated,” they concluded.