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October 26, 2023
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Nonopioid vs. opioid analgesia may be equally effective for pediatric humeral fractures

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Key takeaways:

  • Patients who had nonopioid analgesia showed similar pain scores compared with those who had opioid analgesia after pediatric humeral fracture.
  • Overall, 75.7% of prescribed opioids went unused.
Perspective from Mark Seeley, MD

Published results showed pediatric patients who had closed reduction and percutaneous pinning of a supracondylar humeral fracture and a nonopioid analgesia protocol showed similar pain scores compared with those who had opioid analgesia.

Researchers at Children’s Hospital of Philadelphia performed a multicenter, comparative study to analyze postoperative pain scores from 157 pediatric patients (median age of 6.2 years) who underwent closed reduction and percutaneous pinning of a supracondylar humeral fracture.

opioids
Patients who had nonopioid analgesia showed similar pain scores compared with those who had opioid analgesia after pediatric humeral fracture.Image: Adobe Stock

According to the study, 81 patients received a standard opioid protocol of oxycodone, ibuprofen and acetaminophen, while 76 patients received a nonopioid protocol of ibuprofen and acetaminophen alone. Outcome measures included medication usage and Wong-Baker FACES Scale pain scores, recorded via text message on postoperative days 1 to 7, 10, 14 and 21.

Overall, researchers found low pain scores for both the opioid cohort and the nonopioid cohort, with similar improvements in pain scores from postoperative day 1 to postoperative day 21. Pain scores decreased from 3.6 at postoperative day 1 to 0.2 at postoperative day 21 among patients in the opioid cohort, while pains scores decreased from 3.3 at postoperative day 1 to 0.2 at postoperative day 21 among patients in the nonopioid cohort.

According to the study, 75.7% of prescribed opioids were unused. Researchers noted 28 patients in the opioid cohort (34.6%) took no oxycodone, and 40 patients (49.4%) took one to three total doses across the postoperative period. They also noted patients rarely took opioids after postoperative day 2. One patient in the nonopioid cohort received rescue opioids after presenting to the ED with cast discomfort.

“To improve opioid stewardship, providers and institutions can consider discontinuing the routine prescription of opioids following this procedure,” the researchers wrote in the study.