Talocrural PRP injections yielded no improvements in ankle pain, function at 1 year
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Key takeaways:
- Talocrural PRP injections yielded no improvements in ankle pain or function at 1 year compared with placebo injections.
- Researchers deemed PRP injections to be ineffective for posttraumatic ankle OA.
Patients with ankle osteoarthritis who received intra-articular talocrural platelet-rich plasma injections saw no improvements in ankle pain or function during the course of 1 year, according to published results.
Liam D.A. Paget, MD, and colleagues performed a double-blind, randomized controlled trial of 48 patients (mean age of 54.8 years) who received intra-articular talocrural PRP injections and 52 patients (mean age of 56.4 years) who received saline placebo injections for ankle OA between August 2018 and July 2020.
According to the study, patients in the PRP group received one injection at inclusion and one injection at 6 weeks. Outcome measures included patient-reported American Orthopaedic Foot & Ankle Society scores, VAS pain scores and quality of life.
At 1 year, AOFAS scores were 69 for the PRP group and 67 for the control group. VAS pain scores were 39 in the PRP group and 38 in the control group. Researchers also noted congruent quality of life scores between the groups.
“The results of this study do not support the use of PRP injections for posttraumatic ankle OA, which is common in athletes,” the researchers wrote in the study.
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