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July 12, 2023
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Study: Carpal tunnel syndrome associated with subsequent heart failure

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Key takeaways:

  • Patients older than 60 years of age with carpal tunnel syndrome are at increased risk for new-onset heart failure.
  • Physicians and health care professionals should focus on early detection.

Published results showed patients older than 60 years of age with carpal tunnel syndrome are at increased risk for new-onset heart failure.

Mark Luedde, MD, and colleagues performed a retrospective cohort study of data for 81,898 patients (mean age of 52.9 years) with carpal tunnel syndrome and 81,898 patients (mean age of 52.7 years) without carpal tunnel syndrome. According to the study, the primary outcome measure was heart failure (HF) up to 10 years after the index date. Researchers also analyzed the association between carpal tunnel syndrome and cancer.

Heart failure or heart attack_Adobe Stock_282883897
Patients with carpal tunnel syndrome are at increased risk for heart failure. Image: Adobe Stock

At 10 years, 8.4% of patients with carpal tunnel syndrome and 6.2% of patients without carpal tunnel syndrome had HF. Luedde and colleagues found a significant association between carpal tunnel syndrome and subsequent HF (HR = 1.39). Researchers found no association between carpal tunnel syndrome and HF for patients younger than 61 years of age. They also found no association between carpal tunnel syndrome and cancer.

“The increased rate of HF among patients with [carpal tunnel syndrome] CTS requires attention because HF is a common disease associated with high mortality,” Luedde and colleagues wrote in the study. “Thus, we point to a new role for surgeons together with general practitioners in the early detection of important internal diseases, a chance for better treatment, and an improved prognosis of these diseases,” they wrote.