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July 11, 2023
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Study: Surgeons should consider complications of simultaneous bilateral TKA

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Key takeaways:

  • Simultaneous bilateral TKA was associated with increased complications and readmission compared with unilateral TKA.
  • Surgeons should consider the complications of simultaneous bilateral TKA.

According to results published in the Journal of Bone and Joint Surgery, simultaneous bilateral total knee arthroplasty was associated with increased complications and readmission compared with unilateral TKA.

Researchers at the Keck School of Medicine of University of Southern California analyzed data for 21,044 patients who underwent simultaneous bilateral TKA and 126,264 matched patients who underwent unilateral TKA from 2015 to 2020. According to the study, outcomes included pulmonary embolism (PE), stroke, acute blood loss anemia, transfusion, readmission and in-hospital mortality.

Knee replacement
Simultaneous bilateral TKA was associated with increased complications and readmission. Image: Adobe Stock

At 90 days postoperatively, patients who underwent simultaneous bilateral TKA demonstrated increased risks for PE (adjusted OR = 2.13), stroke (aOR = 2.21), acute blood loss anemia (aOR = 2.06), transfusion (aOR = 7.84) and readmission (aOR = 1.35) compared with patients who underwent unilateral TKA. Researchers found no differences in 90-day in-hospital mortality rates between the groups.

“Orthopedic surgeons should consider indications for a simultaneous bilateral TKA, given the increased risk of postoperative complications,” the researchers wrote in the study. “When simultaneous bilateral TKA is pursued, patient counseling and thorough medical optimization should be performed,” they concluded.