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March 03, 2023
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Study examines corticosteroids vs. PRP treatment for rotator cuff injuries

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Results published in the Journal of Shoulder and Elbow Surgery showed corticosteroid injections have better short-term efficacy, while platelet-rich plasma injections have better long-term efficacy for patients with rotator cuff injuries.

Researchers used the PubMed, Embase and Cochrane databases to perform a systematic review of nine randomized control trials (RCTs) that compared outcomes of corticosteroids vs. PRP for 469 patients with rotator cuff injuries.

Shoulder injury
Corticosteroid injections have better short-term efficacy, while platelet-rich plasma injections have better long-term efficacy for patients with rotator cuff injuries. Image: Adobe Stock

Researchers compared Constant, simple shoulder test (SST) and American Shoulder and Elbow Surgeons scores between the corticosteroid (n = 233) and PRP (n = 236) groups at short-term, midterm and long-term follow-up. According to the study, follow-ups ranged from 3 weeks to 6 months after treatment.

Overall, no differences were found between the corticosteroid and PRP groups at midterm follow-up. Researchers noted the corticosteroid group had improved Constant (mean difference [MD] = –5.08), SST (MD = –0.97) and ASES (MD = –6.67) scores compared with the PRP group at short-term follow-up. However, they found the PRP group had improved recovery of SST (MD = 1.21) and ASES (MD = 6.96) scores compared with the corticosteroid group at long-term follow-up. There were no clinically significant differences in VAS pain scores at any follow-up timepoint between the groups.

“The PRP group showed a beneficial trend, although both groups showed anti-inflammatory effects,” the researchers wrote in the study. “PRP may be more beneficial for long-term recovery because it promotes tendon healing without causing side effects,” they concluded.