Cementless fixation associated with aseptic loosening, revision and reoperation after TKA
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According to the published results, cementless fixation was associated with increased risk of aseptic loosening, revision and reoperation within 2 years after total knee arthroplasty.
Enrico M. Forlenza, MD, and colleagues from Rush University Medical Center analyzed 2-year outcomes of 294,485 patients who underwent primary TKA from January 2015 to December 2018. Of the patients, 3.6% (n = 10,597) underwent cementless TKA.
According to the study, outcome measures were assessed at 90-day, 1-year and 2-year intervals and included aseptic loosening, manipulation under anesthesia, patella resurfacing, periprosthetic fracture, periprosthetic joint infection, revision and reoperation.
Forlenza and colleagues found that compared with cemented TKA, cementless TKA was associated with increased risks of revision for aseptic loosening (odds ratio [OR] = 2.34) and any reoperation (OR = 1.29) at 2 years.
“Although cementless TKA was associated with a shorter length of stay, the small difference observed is unlikely to be clinically important,” the researchers wrote in the study. “While long-term data is needed, surgeons should select implants carefully based on their individual design features and track record,” they added.
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