Alzheimer's Disease/Cognition News

Daily nut consumption among older adults corresponded with a sustained healthy lifespan that lacked adverse health outcomes like dementia or physical disabilities, results of a prospective cohort study suggest.

CHICAGO — High year-to-year cholesterol variability was linked to increased risk for cognitive decline and dementia among older adults, a speaker reported.

Topline results from the phase 3 ReThink-ALZ study of simufilam in mild to moderate Alzheimer’s disease showed the investigational therapeutic did not meet any of its prespecified endpoints.

Many individuals diagnosed with anti-NMDA receptor encephalitis continued to have cognitive issues — particularly with memory and language — up to 3 years after diagnosis, according to a recent study.

Short-term exposure to hormone therapy started within 3 years of menopause was not associated with long-term cognitive impairment or benefit, according to data from the KEEPS Continuation study.

High cardiorespiratory fitness corresponded with better cognitive function and a decreased risk for dementia, according to findings published in the British Journal of Sports Medicine.

In an open-label extension of the CLARITY-AD study, treatment with IV lecanemab was associated with significant improvement in Alzheimer’s disease-related pathology, continuing a positive treatment effect from the randomization phase.

All stages of research on Alzheimer’s disease and related dementias should include increased public and participant involvement so the benefits are seen across diverse populations, according to a position paper in Alzheimer’s & Dementia.

Treatment with oral blarcamesine for older adults with Alzheimer’s disease led to significant slowing of clinical decline compared with placebo at 48 weeks, according to new research presented at CTAD.

Adults aged 50 years and older, particularly women, who experienced obstructive sleep apnea appeared to be at higher risk for dementia, according to a new study published in SLEEP Advances.