Pediatric Neurology News

A clinical-stage biotechnology company will advance a novel autologous chimeric antigen receptor T-cell therapy that targets the immune checkpoint B7-H3 for diffuse intrinsic pontine glioma, or DIPG, a rare incurable pediatric brain tumor.

LOS ANGELES — A wearable, behind-the-ear EEG device is feasible for assessment of sleep patterns in young people with Dravet syndrome, according to a poster presented at the American Epilepsy Society annual meeting.

Topline results from a phase 3 clinical trial showed an investigational gene therapy for young people with spinal muscular atrophy type 2 increased mobility and slowed disease progression, according to a press release from Novartis.

In a newly published paper, the American Academy of Neurology promoted 12 key concepts for patients and providers to successfully promote and maintain brain health.

Healio Neurology looks back at the most popular Q&As with industry and specialty experts from the past year.

LOS ANGELES — Zorevunersen led to 75% to 80% seizure reduction in patients with Dravet syndrome, according to Barry S. Ticho, MD, PhD, FACC, chief medical officer of Stoke Therapeutics.

LOS ANGELES — Treatment with cannabidiol in young people with tuberous sclerosis complex led to significant improvements in several cognitive, behavioral and executive domains, data from ongoing survey show.

LOS ANGELES —Multidisciplinary care and physician- or nurse-led models that eliminate geographic disparities are key to optimal outcomes for youths with epilepsy who are transitioning to adulthood, according to a speaker.

LOS ANGELES — For young people with epilepsy, wearable devices may be a feasible method for tracking the effects of antiseizure medications on the autonomic nervous system, according to a presenter.