Pediatric Neurology News

Plasma biomarkers shed light on concussion-related neuropathology in adolescents who played contact sports in Canada, supporting their use in pathophysiology, according to new research.

Topline data from an ongoing clinical trial of a higher dose regimen of Spinraza in treatment-naive, symptomatic infants with spinal muscular atrophy showed significantly improved motor function at 6 months.

A combination therapy led to significant dystrophin expression and functional improvement in patients with Duchenne muscular dystrophy amenable to exon 51 skipping, according to new data from a phase 1/2 clinical trial.

For infants with Down syndrome, early intervention to address obstructive sleep apnea may lead to better cognitive and behavioral outcomes at 36 months, according to new research from The Lancet.

Over 150 minutes of aerobic exercise a week following a concussion improved sleep quality in adolescents, study results published in The Journal of Head Trauma Rehabilitation showed.

In young male American football players, concussion symptoms and severity were higher for those who sustained the injury on natural grass compared with artificial turf, according to new research in the Clinical Journal of Sports Medicine.

PHILADELPHIA — In this video, Cassie Kline, MD, MAS, discusses the results of the PNOC005 trial she presented at International Symposium on Pediatric Neuro-Oncology.

PHILADELPHIA — In this video, Cassie Kline, MD, MAS, discusses the results of the PNOC016 trial she presented at International Symposium on Pediatric Neuro-Oncology.

An investigational, fully human monoclonal antibody developed as a muscle-targeted therapy for spinal muscular atrophy showed sustained motor function improvements at 48 months, according to the manufacturer.