Alzheimer's Disease/Cognition News

A clinical diagnostics company and biotech firm have announced a partnership to develop a blood-based tau pathology test that would assist in the diagnosis of Alzheimer’s disease.

In a cohort of community-dwelling older adults, poor sleep quality was indicative of incident motoric cognitive risk syndrome as well as increased physical and mental disability, according to research published in Neurology.

Poor sleep patterns in early midlife appeared to be associated with advanced brain age in late midlife, suggesting the importance of early sleep interventions to preserve brain health, according to study results.

Biogen Inc. and Neomorph Inc. have announced a partnership geared toward research and development of molecular glue degraders to address protein accumulation related to Alzheimer’s disease and other neurologic conditions.

Plasma pTau181 in combination with ApoE4 assays registered a high degree of accuracy in ruling out patients with a low probability of amyloid pathology in the early stages of Alzheimer’s disease, according to a poster presentation at CTAD.

The International Working Group has updated diagnostic guidelines for Alzheimer’s disease to include individuals with normal cognition who test positive for core biomarkers indicative of disease pathology.

Treatment with non-invasive, personalized repetitive transcranial magnetic stimulation in those with mild to moderate Alzheimer’s resulted in a 44% slowing of disease progression at 52 weeks, according to the manufacturer.

Consuming a diet with more plant-based foods and the right kind of fats while engaging in daily exercise are sure-fire paths to maintaining brain health, according to speakers at the Lifestyle Medicine Conference.

ADx NeuroSciences and Alamar Biosciences have announced a partnership to develop customized biomarker assays for companies that advance novel therapeutics for a range of neurological conditions.

Cardiovascular health of middle-aged adults was significantly associated with the risk of poor brain health later in life, according to a study published in Neurology.