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Neuro-Oncology News
CAR T-cell therapy produces ‘jaw dropping’ results for deadly pediatric brain tumors
Chimeric antigen receptor T-cell therapy can reduce tumor burden and improve neurologic function for patients with certain brain and spinal cord cancers, a first-in-human clinical trial showed.
De-escalated adjuvant chemotherapy effective for high-risk retinoblastoma
A shortened adjuvant chemotherapy regimen improved outcomes for infants with unilateral pathologic high-risk retinoblastoma, according to study results.
Addition of veliparib to temozolomide fails to extend survival in glioblastoma
The addition of veliparib to adjuvant temozolomide failed to improve OS for patients with newly diagnosed, MGMT-hypermethylated glioblastoma, according to randomized phase 2/phase3 study results.
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MS linked to greater risk for certain cancers
People with MS had an increased risk for bladder, brain and cervical cancers compared with people without MS, according to a new study in Neurology, the medical journal of the American Academy of Neurology.
Trial to assess personalized vaccine for aggressive brain tumors
A first-in-human clinical trial will assess the safety of a personalized vaccine to treat diffuse hemispheric glioma, an aggressive brain tumor.
Young children treated for brain tumors less ready for school than their peers
Young children who underwent treatment for brain tumors had lower academic readiness scores than their peers, according to results of a prospective longitudinal trial.
Drug shows ‘very promising’ activity in breast cancer brain metastases
Sacituzumab govitecan-hziy exhibited efficacy as therapy for two traditionally difficult-to-treat populations, according to results of a window-of-opportunity trial.
FDA clears cyber device, AI system to address glioblastoma
An Alabama-based company announced that the FDA has granted 510(k) clearance to its cyber device and AI system, which are designed to improve efficiency and accuracy of glioblastoma care.
VIDEO: Study investigates use of oncolytic measles virus to treat pediatric brain tumors
PHILADELPHIA — In this video, Cassie Kline, MD, MAS, discusses the results of the PNOC005 trial she presented at International Symposium on Pediatric Neuro-Oncology.
VIDEO: Study investigates novel therapy for penetration of pediatric brain tumors
PHILADELPHIA — In this video, Cassie Kline, MD, MAS, discusses the results of the PNOC016 trial she presented at International Symposium on Pediatric Neuro-Oncology.
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