VIDEO: Cellular senescence identified in patients with MS

CHICAGO — Stephen J. Crocker, PhD, associate professor of neuroscience at University of Connecticut School of Medicine, discusses the influence of aging on MS and remyelination, as well as the process of cellular senescence, at ANA 2022.
“When these cells are differentiated to a neural phenotype, or neural stem cell, they exhibit markers of cellular senescence, which is proinflammatory and also limiting for the ability ... of oligodendrocytes to produce myelin,” he said.