HemOnc Today Current Issue

The following articles appeared in the print edition of HemOnc Today.

Table of Contents

• Technological advances signal shift toward individualized breast cancer screening
• Fertility preservation ‘central’ to health, wellness of AYA patients Leonard S. Sender, MD; Keri B. Zabokrtsky, MS; Julie A. Messina, PA-C
• American Thyroid Association elects board members
• A new angle on ‘patient experience’ in oncology: The challenge of patient-reported outcomes John Sweetenham, MD, FRCP, FACP
• FDA approves Cyramza for treatment of advanced gastric cancer
• FDA approves Avastin for platinum-resistant, recurrent ovarian cancer
• FDA grants orphan drug status to MM-141 for pancreatic cancer
• FDA grants breakthrough therapy designation to Keytruda for NSCLC
• FDA grants orphan drug status to Glassia for GVHD
• ODAC rejects panobinostat for relapsed multiple myeloma
• FDA grants fast track designation to TH-302 for metastatic soft tissue sarcoma
• State of the science: High-priority transplant trials for lymphoma Hemant Murthy, MD; William Wood, MD
• Pertuzumab regimen delayed onset of CNS metastases in breast cancer
• Chemotherapy ‘vastly underutilized’ in bladder cancer
• Frequency of TERT promoter mutations in cutaneous melanoma varied by subtype
• RET mutation identified as potential novel target in SCLC
• High-mitotic rate melanoma linked to patient, tumor characteristics
• Efficacy of VTE chemoprophylaxis in otolaryngology patients varied by subgroup
• High radioactive iodine-131 exposure dose linked to aggressive thyroid cancer
• More than 8 million American women unscreened for cervical cancer
• Risk assessment models predicted VTE risk in high-grade gliomas
• Zoledronic acid plus everolimus improved outcomes in renal cell carcinoma
• Adjuvant FOLFOX extended DFS in locally advanced rectal cancer
• As-needed rituximab controlled follicular lymphoma with less treatment
• ATRA plus arsenic trioxide improved quality of life in acute promyelocytic leukemia
• Barrett’s esophagus associated with increased risk for colon polyps
• Chronic dental trauma potential oral cavity cancer carcinogen
• CMS draft guidance allows access to lung cancer screening, requires safeguards Edward S. Kim, MD, MBA, FACP, FASCO
• Contralateral prophylactic mastectomy patients reported confidence with decision
• Decision to undergo post-mastectomy breast reconstruction varied significantly by race, age
• Early SCID identification improved survival after HSCT
• Everolimus–exemestane combination failed to significantly extend OS in advanced breast cancer
• Familial pancreatic cancer increased risk for other malignancies in kindred
• Gemcitabine regimen effective in relapsed, refractory aggressive lymphomas
• Genetic determinant identified for increased melanoma risk
• Inadequate bladder cancer biopsy linked to increased mortality
• Johns Hopkins makes staff announcements
• Long-segment Barrett’s esophagus linked to increased cancer risk
• Low-molecular-weight heparin more cost-effective than unfractionated heparin for VTE prevention
• Olaparib maintenance for ovarian cancer most effective in women with BRCA mutations
• Platinum-based chemotherapy extended OS in BRCA-associated pancreatic ductal adenocarcinoma
• Provider names chief science officer
• Radium-223 dichloride effective in CRPC, regardless of prior docetaxel
• Recreational physical activity reduced risk for postmenopausal breast cancer
• SLNB did not improve survival in head and neck melanoma
• Somatic mutations in myelodysplastic syndrome linked to shorter survival after HSCT
• Studies conflict over bleeding risk with dabigatran, warfarin
• Target-specific oral anticoagulants reduced risk for bleeding in VTE, atrial fibrillation
• FOLFOXIRI plus bevacizumab improved outcomes, increased toxicity in metastatic colorectal cancer
• Increased hospital-based services for ovarian cancer highlight need for end-of-life plans
• Low-risk adenoma removal associated with reduced colorectal cancer mortality
• Maintenance pazopanib extended PFS, not OS in ovarian cancer
• Outcomes in primary myelofibrosis varied greatly based on mutation status
• Higher carfilzomib dose induced durable response in multiple myeloma
• Patients with lung, colon cancers often not informed about clinical trials
• Indiana University School of Medicine appoints chief of radiation
• Mount Sinai appoints co-director of breast center
• NYU Langone names cancer center director
• Roswell Park names cancer center director
• UC Davis appoints chair of department of public health sciences
• American Indians, Alaskan Natives experienced shorter cancer survival, even with equal access to care
• Serum metabolites may serve as biomarker for early lung cancer detection
• Differentiated thyroid carcinoma benefitted from total/near-total thyroidectomy followed by RAI
• HPV vaccination rates among girls lowest in states with highest cervical cancer rates
• Radioactive iodine improved survival in differentiated thyroid carcinoma
• Survival benefit found with RAI, all sizes of papillary thyroid carcinoma tumors
• Family history influenced risk for triple-negative breast cancer in women of Mexican descent
• Videos increased clinical trial awareness among Latina patients with breast cancer