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Gastrointestinal Cancer News
Immunotherapy alone could replace surgery in cancer subset
Neoadjuvant immunotherapy alone resulted in significant treatment response among most patients with mismatch-repair-deficient early-stage solid tumors, according to study results.
New AACE guidance highlights treatments, genetic testing for MEN1-associated tumors
A consensus statement published in Endocrine Practice examines how health care professionals should approach treating and screening people with tumors associated with multiple endocrine neoplasia type 1.
‘Remarkable’ improvement in colorectal cancer screening, death rates with outreach program
SAN DIEGO — Screening rates for colorectal cancers were doubled, CRC-related mortality cut in half and racial disparities nearly eliminated with a 20-year outreach program, according to study results presented at Digestive Disease Week.
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Smoking status provides ‘critical adjustment opportunity’ in care for patients with cancer
Smoking status added to the National Cancer Database for patients diagnosed with cancer in 2023 revealed variations in sociodemographic and socioeconomic factors, according to a research letter in JAMA Oncology.
Confirmatory study delay after FDA accelerated approval should be ‘cautionary sign’
Cancer drugs that received accelerated approval from the FDA gained regular approval significantly faster if their confirmatory trials demonstrated meaningful clinical benefits, according to results of a retrospective study.
Tumor-infiltrating lymphocyte therapy effective against common gastrointestinal cancers
A novel approach to tumor-infiltrating lymphocyte therapy yielded higher response rates among patients with metastatic gastrointestinal cancers than prior strategies, according to results of a phase 2 trial.
‘Time to rethink’ when patients with cancer enroll in early-phase trials, researchers argue
Patients with advanced cancer should be enrolled in early phase clinical trials during favorable points in their disease rather than after exhausting standard-of-care treatments, according to a paper published in JCO Oncology Practice.
ASTRO's first anal cancer guideline addresses 'complicated’ treatments from ‘holistic’ view
The American Society for Radiation Oncology has issued its first clinical guideline on the use of radiation therapy to treat adults with anal cancer.
Cancer mortality rates continue to decrease, but at a slower pace
Cancer mortality gradually declined over the past 2-plus decades, although the rate slowed between 2019 and 2022, according to results of the Annual Report to the Nation on the Status of Cancer.
Guidance aims to ensure phase 3 cancer trials are clinically valid, meaningful
A grassroots organization that formed with the goal of recalibrating cancer care around patient needs issued guidance intended to improve the design of randomized phase 3 trials.
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Headline News
Gene-based blood test may predict melanoma recurrence
April 30, 20252 min read -
Headline News
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April 29, 20253 min read -
Headline News
VIDEO: Nutrition, exercise may help preserve muscle mass during GLP-1 receptor agonist use
April 26, 20252 min watch