VIDEO: When to consider CML diagnosis in primary care settings

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The diagnosis has become much, much easier. Maybe the challenge is trying to see if we can eventually get to a point where you can diagnose CML without doing multiple bone marrows. I don't think we're there yet, because the bone marrow still gives you an understanding of the proliferative state of the CML and whether or not there are too many blasts, whether it looks like it's evolving at diagnosis. But, you know, in an ideal world, that would be the place.

I think the only other caveat to that is, you know, CML is often diagnosed in people who are otherwise healthy, and so, you know, an elevated neutrophil count can happen with infection, can happen with other non-malignant causes, and so it's more for the primary care docs to, you know, say, "Wait a minute, something's not right here," and if someone has a spleen or something else that goes along with it, that they think about doing the tests. It's not that it's hard to diagnose, it's more about, you know, having it top of mind when that's not something you see every day.