• 1. Immune checkpoints play a vital role in maintaining peripheral tolerance and immune system homeostasis.
• Your Colleagues Responded
• A. True

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• B. False

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• 2. What is the second signal in the two-signal model of T cell activation?
• Your Colleagues Responded
• A. T cell receptors bind to peptides on major histocompatibility complex

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• B. PD-1 binding to PD-L1

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• C. CD28 binding to B7 molecule

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• D. CTLA-4 binding to B7 molecule
  
  

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• 3. Which receptor has a high expression pattern in multiple myeloma cells, but lacks expression in healthy tissue?
• Your Colleagues Responded
• A. LAG3

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• B. SLAMF7
  

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• C. CD28

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• D. PD-1

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• 4. Costimulation of these two coinhibitory receptors is of interest in transplant patients and those with autoimmune disease:
• Your Colleagues Responded
• A. CLTA-4 and PD-1

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• B. SLAMF7 and PD-1

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• C. CD28 and CTLA-4

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• D. ICOS and PD-1

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• 5. LAG3 is a costimulatory signaling pathway.
• Your Colleagues Responded
• A. True

  0%
• B. False

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