• 1. Consideration for genomic testing depends on which of the following factors? Select all that apply.
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• A. Stage

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• B. Treatment history

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• C. Type of cancer

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• D. Smoking status

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• E. All of the above

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• 2. A melanoma patient diagnosed at Stage IIB is not considered a candidate for routine genomic testing?
• Your Colleagues Responded
• A. True

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• B. False

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• 3. A patient with Stage IV pharyngeal cancer is about to begin standard treatment for head and neck squamous cell carcinoma. Before starting his platinum-based regimen, genomic testing should be performed because predictive markers may help determine response.
• Your Colleagues Responded
• A. True

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• B. False

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• 4. All of the following factors may be considered when choosing a genomic testing strategy for a newly diagnosed patient, except for:
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• A. Biopsy material available

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• B. Health status of patient

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• C. Financial

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• D. Treatment goal

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• E. Treatment history

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• 5. List the following genomic assays in order of increasing complexity: (A) targeted hot-spot sequencing (B) companion diagnostics (C) comprehensive genomic profiling.
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• A. C, B, A

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• B. B, A, C

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• C. C, A, B

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• D. A, C, B

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• 6. Specimen requirements should not be reviewed when choosing a commercial genomic testing platform.
• Your Colleagues Responded
• A. True

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• B. False

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• 7. Tissue biopsies remain the gold standard source of tumor material for genomic testing.
• Your Colleagues Responded
• A. True

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• B. False

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• 8. Some of the challenges that may be faced when interpreting a genomic report include which of the following:
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• A. Differentiating “driver” and “passenger” mutations

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• B. Understanding mutation categorizations (e.g. pathogenic vs. benign)

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• C. Determining what is clinically actionable

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• D. All of the above

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• 9. The importance of precision medicine in the future of healthcare has been acknowledged by the U.S. government through recently implemented research and funding initiatives.
• Your Colleagues Responded
• A. True

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• B. False

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