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December 10, 2021
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Supportive therapies ‘essential’ to mitigate aromatase inhibitor-related adverse effects

Supportive therapies ‘essential’ to mitigate aromatase inhibitor-related adverse effects

Supportive therapies are necessary to help ensure patients adhere to aromatase inhibitor treatment, according to study results presented at San Antonio Breast Cancer Symposium.

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December 10, 2021
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Nivolumab plus ipilimumab shows benefit in metastatic HER2-negative breast cancer

Nivolumab plus ipilimumab shows benefit in metastatic HER2-negative breast cancer

Nivolumab plus ipilimumab induced durable responses among a small cohort of women with high tumor mutational burden metastatic HER2-negative breast cancer, according to study results presented at San Antonio Breast Cancer Symposium.

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December 10, 2021
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Aromatase inhibitors benefit certain premenopausal women with early breast cancer

Aromatase inhibitors benefit certain premenopausal women with early breast cancer

Aromatase inhibitors may reduce breast cancer recurrence compared with tamoxifen for certain postmenopausal women with breast cancer, according to study results presented at San Antonio Breast Cancer Symposium.

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December 10, 2021
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Tumor biology predicts breast cancer treatment outcomes more than race

Tumor biology predicts breast cancer treatment outcomes more than race

Race did not significantly predict response to treatment outcomes among women with high-risk breast cancer, according to study results presented at San Antonio Breast Cancer Symposium.

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December 10, 2021
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Postmenopausal women lose about 10% of femoral neck BMD over 25 years

Postmenopausal women lose about 10% of femoral neck BMD over 25 years

A cohort of postmenopausal women from Finland had a bone mineral density decrease of about 10% during a follow-up period of 25 years, according to findings published in the Journal of Bone and Mineral Research.

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December 09, 2021
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Metformin does not improve outcomes in early breast cancer

Metformin does not improve outcomes in early breast cancer

Metformin did not improve outcomes for most patients with early breast cancer, according to study results presented at San Antonio Breast Cancer Symposium.

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December 09, 2021
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Entinostat plus exemestane improves PFS in hormone receptor-positive advanced breast cancer

Entinostat plus exemestane improves PFS in hormone receptor-positive advanced breast cancer

The addition of entinostat to exemestane improved PFS for patients with hormone receptor-positive, HER2-negative advanced breast cancer, according to randomized phase 3 study results presented at San Antonio Breast Cancer Symposium.

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December 08, 2021
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Tamoxifen-induced PI3 kinase pathway activation may increase uterine cancer risk

Tamoxifen-induced PI3 kinase pathway activation may increase uterine cancer risk

Patients with breast cancer who developed tamoxifen-associated uterine cancer had fewer phosphatidylinositol 3-kinase pathway mutations than those with de novo cases, according to results presented at San Antonio Breast Cancer Symposium.

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December 08, 2021
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Palbociclib regimen fails to extend invasive DFS in early breast cancer

Palbociclib regimen fails to extend invasive DFS in early breast cancer

The addition of palbociclib to adjuvant endocrine therapy did not extend invasive DFS for patients with early hormone receptor-positive, HER2-negative breast cancer, according to results presented at San Antonio Breast Cancer Symposium.

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December 07, 2021
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Exercise protocol enhanced training response for women in cardiac rehabilitation

Exercise protocol enhanced training response for women in cardiac rehabilitation

An exercise protocol that combined high-intensity interval training and intensive lower-extremity resistance training enhanced training response in women undergoing cardiac rehabilitation compared with standard exercise training.

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