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Tyrosine Kinase Inhibitor

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August 18, 2022
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TYK2 inhibitors may offer pathway for more comprehensive inflammation therapy

TYK2 inhibitors may offer pathway for more comprehensive inflammation therapy

The emergence of drugs inhibiting the JAK-STAT pathway has culminated in tyrosine kinase 2 inhibitors targeting psoriatic arthritis, lupus and other indications, noted a presenter at the 2022 Association of Women in Rheumatology conference.

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July 06, 2022
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Remibrutinib reduces rescue medication use among adults with chronic spontaneous urticaria

Remibrutinib reduces rescue medication use among adults with chronic spontaneous urticaria

Remibrutinib reduced the need for rescue medication and improved symptoms among patients with chronic spontaneous urticaria, according to a study presented at the European Academy of Allergy and Clinical Immunology Hybrid Congress.

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June 22, 2022
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Cabozantinib plus atezolizumab shows potential in advanced urothelial carcinoma

CHICAGO — Cabozantinib plus atezolizumab showed encouraging clinical activity in patients with inoperable locally advanced or metastatic urothelial carcinoma, according to data from the COSMIC-021 study.

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June 09, 2022
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Asciminib safer, more effective than bosutinib in chronic-phase chronic myeloid leukemia

Asciminib safer, more effective than bosutinib in chronic-phase chronic myeloid leukemia

CHICAGO — Asciminib continued to confer superior efficacy and better safety and tolerability than bosutinib among patients with chronic-phase chronic myeloid leukemia, according to study results presented during ASCO Annual Meeting.

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April 19, 2022
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VIDEO: Should pharmacists consider albumin level when giving certain TKIs?

VIDEO: Should pharmacists consider albumin level when giving certain TKIs?

BOSTON – In this video interview, Christy S. Harris, PharmD, BCOP, FHOPA, talked about poster sessions presented at Hematology/Oncology Pharmacy Association Annual Meeting.

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April 19, 2022
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VIDEO: Immunotherapy ‘trying to move the needle forward’ in upper GI cancer care

VIDEO: Immunotherapy ‘trying to move the needle forward’ in upper GI cancer care

BOSTON – Christy S. Harris, PharmD, BCOP, FHOPA, discussed a presentation on the role of immunotherapy in upper gastrointestinal cancer and how it’s “trying to move the needle forward” in care.

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March 16, 2022
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AHA guidance identifies potential drug-to-drug interactions between CV, cancer medications

AHA guidance identifies potential drug-to-drug interactions between CV, cancer medications

In a recent American Heart Association scientific statement, a committee provided an overview of drug-to-drug interactions between cancer drugs and commonly used CV medications.

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February 28, 2022
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Questions remain about best front-line treatment in mantle cell lymphoma

As new therapeutic options for mantle cell lymphoma emerge, physicians are learning where they best fit into the treatment armamentarium.

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February 01, 2022
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VIDEO: Challenges in treating EGFR-mutated lung cancer

VIDEO: Challenges in treating <i>EGFR</i>-mutated lung cancer

In this video, Erminia Massarelli, MD, PhD, MS, co-director of the lung cancer and thoracic oncology program, and associate professor in the department of medical oncology and therapeutics research at City of Hope Cancer Center in Duarte, California, discusses challenges in treating EGFR-mutated lung cancer.

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February 01, 2022
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VIDEO: Evolution of biomarker testing in EGFR-mutated lung cancer

VIDEO: Evolution of biomarker testing in <i>EGFR</i>-mutated lung cancer

In this video, Erminia Massarelli, MD, PhD, MS, co-director of the lung cancer and thoracic oncology program, and associate professor in the department of medical oncology and therapeutics research at City of Hope Cancer Center in Duarte, California, discusses how diagnosis or biomarker testing of EGFR-mutated lung cancer has evolved.

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