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Tyrosine Kinase Inhibitor

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February 01, 2022
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VIDEO: Treating lung cancer with EGFR exon 20 mutation

VIDEO: Treating lung cancer with <i>EGFR</i> exon 20 mutation

In this video, Erminia Massarelli, MD, PhD, MS, co-director of the lung cancer and thoracic oncology program, and associate professor in the department of medical oncology and therapeutics research at City of Hope Cancer Center in Duarte, California, discusses treatment variations for rarer mutations such as EGFR exon 20 insertions.

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February 01, 2022
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VIDEO: Approaching EGFR exon 19 deletion, L858R mutations in lung cancer

VIDEO: Approaching <i>EGFR</i> exon 19 deletion, <i>L858R</i> mutations in lung cancer

Erminia Massarelli, MD, PhD, MS, co-director of the lung cancer and thoracic oncology program, and associate professor in the department of medical oncology and therapeutics research at City of Hope Cancer Center in Duarte, California, spoke with Healio about treatment approaches for EGFR 19 deletions and EGFR L858R in small cell lung cancer.

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February 01, 2022
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VIDEO: Treatment options for early-stage EGFR-mutated non-small cell lung cancer

VIDEO: Treatment options for early-stage <i>EGFR</i>-mutated non-small cell lung cancer

In this video, Erminia Massarelli, MD, PhD, MS, co-director of the lung cancer and thoracic oncology program, and associate professor in the department of medical oncology and therapeutics research at City of Hope Cancer Center in Duarte, California, highlights treatment options for EGFR-mutated lung cancer.

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December 27, 2021
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Communication, education key to optimal management of chronic myeloid leukemia

Communication, education key to optimal management of chronic myeloid leukemia

In the last two decades, the approval of multiple tyrosine kinase inhibitors for chronic myeloid leukemia has vastly improved the treatment landscape for patients.

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November 04, 2021
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Targeted therapy: An integral component of HER2-positive breast cancer care

Targeted therapy: An integral component of HER2-positive breast cancer care

Targeted therapies in HER2-positive breast cancer are integral to the success of treatment outcomes in this patient population.

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November 03, 2021
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VIDEO: Prior TKI therapy did not affect response to gilteritinib in AML

VIDEO: Prior TKI therapy did not affect response to gilteritinib in AML

In this video, Alexander Edward Perl, MD, MS, spoke with Healio about a study assessing the outcome of patients with acute myeloid leukemia who received gilterintib with prior midostaurin or sorafenib therapy.

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September 16, 2021
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FDA approves Exkivity for NSCLC subset

FDA approves Exkivity for NSCLC subset

The FDA approved mobocertinib for treatment of certain patients with non-small cell lung cancer.

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July 07, 2021
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VIDEO: Acalabrutinib equal to ibrutinib in PFS with less cardiotoxicity

VIDEO: Acalabrutinib equal to ibrutinib in PFS with less cardiotoxicity

In this video, John C. Byrd, MD, a professor at The Ohio State University, discussed the study he presented at ASCO21 that showed progression-free survival rates were equal among patients with CML treated with acalabrutinib vs. ibrutinib.

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June 29, 2021
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NSCLC treatment failure increases with genomic aberration, never-smokers, non-resection

Tyrosine kinase inhibitor-sensitive genomic aberrations, unresected tumors and not smoking were associated with increased treatment failure in non-small cell lung cancer, according to a presentation at the virtual ASCO annual meeting.

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May 21, 2021
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VIDEO: Phase 3 data on deucravacitinib 'quite compelling'

VIDEO: Phase 3 data on deucravacitinib 'quite compelling'

In this video, Joel M. Gelfand, MD, MSCE, professor of dermatology and epidemiology at the University of Pennsylvania Perelman School of Medicine, spoke with Healio about research on deucravacitinib presented at AAD VMX 2021.

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