Scleroderma News

WASHINGTON — CD19 chimeric antigen receptor T-cell therapy led to remission, or ceased disease progression, over a period of up to 15 months in 35 patients with lupus, myositis and systemic sclerosis, according to data.

EULAR has released new recommendations on the treatment of systemic sclerosis, advancing new treatments and updated approaches to key manifestations such as skin and lung fibrosis.

WASHINGTON — Patients with autoimmune rheumatic diseases who withhold methotrexate for 2 weeks after receiving the recombinant herpes zoster vaccine demonstrate improved humoral response, according to data presented at ACR Convergence 2024.

Patients with systemic sclerosis demonstrate lower bone mineral density compared with the general population, with significant differences reported in women aged younger than 45 years, according to data published in Rheumatology.

Systemic sclerosis is the most challenging diagnosis to make among rheumatic and autoimmune conditions, according to 91% of respondents in a market analysis from Spherix Global Insights.

SAN DIEGO — Clinicians managing systemic sclerosis should focus on treating “what is treatable” in each organ that is involved, according to data presented at the 2024 Congress of Clinical Rheumatology West.

SAN DIEGO — All patients with systemic sclerosis should be screened for pulmonary arterial hypertension and interstitial lung disease, according to a speaker at the 2024 Congress of Clinical Rheumatology West.

SAN DIEGO — Regulatory trials of chimeric antigen receptor T-cell therapies for autoimmune diseases could be successful with a focus on patients with severe disease and strict endpoints, according to a speaker.

The FDA has granted orphan drug designation to AISA-021, a fourth-generation calcium channel blocker, for the treatment of systemic sclerosis, according to a press release from Aisa Pharma.

Radiotherapy poses no significant risks for worsening disease in patients with systemic sclerosis, but entails “variable risk” for both acute and late toxicities, according to data published in The Journal of Rheumatology.