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May 20, 2022
48 min listen
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SAPHO Part 1

What is SAPHO? What does the ‘H’ stand for, again? This episode explores some basics about the condition and delves into the history of how this disease came to be.

  • Intro :01
  • Welcome to another exciting episode of Rheuminations :11
  • About today’s episode :17
  • What does the acronym ‘SAPHO’ stand for? :37
  • How do you define this condition? 2:35
  • So, what is SAPHO syndrome? 4:59
  • Are any of the letters specific for SAPHO syndrome? 15:20
  • How the puzzle pieces were put together 15:48
  • Over the next ensuing decades, when did we start realizing that patients could have dermatologic manifestations? 23:00
  • So, what about hyperostosis? 30:46
  • Why isn’t the Sonozaki group getting the credit? 39:22
  • So, how did we get SAPHO? 40:26
  • How did they get 85 patients? 42:50
  • We went through a lot in this paper 45:29
  • Next episode preview 46:29
  • Thanks for listening 47:03

We’d love to hear from you! Send your comments/questions to Dr. Brown at rheuminationspodcast@healio.com. Follow us on Twitter @HRheuminations @AdamJBrownMD @HealioRheum and be sure to check out Rheum + Boards – your destination for rheumatology education and quizzes!

References:

Chamot AM, et al. Rev Rheum Mal Osteoartic. 1987;54:187-196.

Giedion A, et al. Ann Radiol (Paris) 1972;15:329-342.

Köhler H, et al. Ann Intern Med. 1977;87:192-194.

 

Nguyen MT, et al. Semin Arthritis Rheum. 2012;42:254-265.

 

Raposo I, Torres T. Am J Clin Dermatol. 2016;17:349-358. 

Romani M, et al. Clin Podiatr Med Surg. 2021;38:541-552. 

Sonozaki H, et al. Ann Rheum Dis. 1981;40:547-553.

Windom RE, et al. Arthritis Rheum. 1961;4:632-635. 

Sources/Disclosures

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Disclosures: Brown reports no relevant financial disclosures.