SAPHO Part 1

ByAdam J. Brown, MD

What is SAPHO? What does the ‘H’ stand for, again? This episode explores some basics about the condition and delves into the history of how this disease came to be.

Intro :01
Welcome to another exciting episode of Rheuminations :11
About today’s episode :17
What does the acronym ‘SAPHO’ stand for? :37
How do you define this condition? 2:35
So, what is SAPHO syndrome? 4:59
Are any of the letters specific for SAPHO syndrome? 15:20
How the puzzle pieces were put together 15:48
Over the next ensuing decades, when did we start realizing that patients could have dermatologic manifestations? 23:00
So, what about hyperostosis? 30:46
Why isn’t the Sonozaki group getting the credit? 39:22
So, how did we get SAPHO? 40:26
How did they get 85 patients? 42:50
We went through a lot in this paper 45:29
Next episode preview 46:29
Thanks for listening 47:03

We’d love to hear from you! Send your comments/questions to Dr. Brown at rheuminationspodcast@healio.com. Follow us on Twitter @HRheuminations @AdamJBrownMD @HealioRheum and be sure to check out Rheum + Boards – your destination for rheumatology education and quizzes!

References:

Chamot AM, et al. Rev Rheum Mal Osteoartic. 1987;54:187-196.

Giedion A, et al. Ann Radiol (Paris) 1972;15:329-342.

Köhler H, et al. Ann Intern Med. 1977;87:192-194.

Nguyen MT, et al. Semin Arthritis Rheum. 2012;42:254-265.

Raposo I, Torres T. Am J Clin Dermatol. 2016;17:349-358.

Romani M, et al. Clin Podiatr Med Surg. 2021;38:541-552.

Sonozaki H, et al. Ann Rheum Dis. 1981;40:547-553.

Windom RE, et al. Arthritis Rheum. 1961;4:632-635.

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Sources/Disclosures

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