VIDEO: Microbiome still holds ‘more questions than answers’ for autoimmune disease
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In a Healio video exclusive, Leonard Calabrese, DO, chief medical editor of Healio Rheumatology, offered his insights for our November issue, led by a cover story examining the connection between the gut microbiome and rheumatic disease.
“The cover story is on advances in the microbiome [with] some of the biggest names working in the space,” Calabrese said. “I do believe that there are still far, far many more questions than answers, but we are making in-roads and getting data from humans, particularly in lupus.”
The cover story features contributions from a host of experts, including John M. Davis, III, MD, Kristine Kuhn, MD, Renuka Nayak, MD, and Gregg Silverman, MD, discussing new data opening doors to the possibility of a causal relationship between dysbiosis and autoimmune disease.
In addition to the cover story, the November issue includes recent coverage of new data regarding the link between COVID-19 and autoimmunity, as well as the role of autoantibody formation during the acute phase of infection. Can COVID-19 cause new-onset or reactivated autoimmune disease and do these autoantibodies play a direct pathogenic role in disease manifestation?
“We address the question of whether COVID-19 actually precipitates autoimmunity in the wake of the infection,” Calabrese said. “We were so privileged to have Jean-Laurent Casanova, MD, PhD, one of the great immunologists and geneticists in the field, comment on this issue.”
Also leading our coverage this month is data presented at the recent Congress of Clinical Rheumatology West meeting, in which Yvonne C. Lee, MD, MMSc, argued that non-pharmacologic approaches to pain management in rheumatology, like exercise and meditation, can actually be superior to pharmacologic strategies.
“This is one of my favorite areas — nonpharmacologic strategies for pain in rheumatic disease patients, in which we discuss the immunology of wellness,” Calabrese said. “How to eat, how to sleep, how to exercise and how to handle your stress.”
Calabrese invited readers to dig into the November issue of Healio Rheumatology by clicking here.
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