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Study: Patients with ankylosing spondylitis at greater odds for complications after THA
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Compared with controls, patients with ankylosing spondylitis had greater odds for complications after total hip arthroplasty, according to results of a recently published study.
“Although [total hip arthroplasty] THA remains the gold standard for treatment of end-stage degenerative disease of the hip, there remain non-trivial rates of complications,” the researchers wrote. “Accordingly, it is important to identify the potential risk factors, eliminate or reduce the effects of modifiable risk factors, and include unmodifiable risks into the decision of when and whether to operate.”
Investigators assessed 1,006 Medicare patients diagnosed with ankylosing spondylitis (AS) and who underwent THA between 2005 and 2012. Researchers found patients with AS had an increased risk for THA component breakage 90 days after surgery (risk ratio = 2.5), as well as at 2 years after surgery (risk ratio = 1.99). In addition, the risk for periprosthetic hip dislocation increased after 90 days (risk ratio = 1.44), at 2 years (risk ratio = 1.67) and for the overall follow-up (risk ratio = 1.49). Furthermore, THA revision risk increased after 90 days (risk ratio = 1.46) and at 2 years (risk ratio = 1.69), as well as for overall follow-up (risk ratio = 1.51).
“The data herein demonstrate a clear increase in perioperative and postoperative risk for complication in the AS population that should be considered when discussing treatment with patients and constructing an operative plan,” the researchers wrote. – by Will Offit
Disclosures: The researchers report no relevant financial disclosures.
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