Reliability, accuracy varies for radiographic assessment of knee OA prior to knee replacement
Although results from this randomized control study showed variable intra-reader and inter-reader agreement on individual radiographic characteristics between a radiologist and non-clinicians who were trained to evaluate radiographic aspects of knee osteoarthritis, there was substantial reliability regarding the Kellgren-Lawrence grade and Osteoarthritis Research Society summary score.
Researchers enrolled 309 patients who underwent primary total knee replacement and were diagnosed with osteoarthritis (OA). A radiologist trained three non-clinicians to evaluate radiographs to identify characteristics of OA. Before total knee replacement, the non-clinicians and radiologist looked at the preoperative films of 36 patients. The Kellgren-Lawrence (KL) grade and Osteoarthritis Research Society (OARSI) summary score were also calculated. Investigators assessed intra-reader and inter-reader reliability using the intraclass correlation coefficient (ICC) and the weighted kappa statistic.
Results for the three non-clinicians showed the intra-reader reliability ranged from 0.40 to 1.0 for the individual characteristics and ranged from 0.72 to 1 for the KL grade. For the OARSI score, the ICC ranged from 0.89 to 0.98. Investigators noted the inter-reader reliability ranged from 0.45 to 0.94 for the individual aspects of the radiographs, and the inter-reader reliability for the KL grade ranged from 0.66 to 0.97. For the OARSI score, the ICC ranged from 0.87 to 0.96.
According to researchers, the inter-reader reliability ranged from 0.56 to 0.85 for the KL grade between the radiologist and the non-clinicians. The ICC for the OARSI summary score ranged from 0.79 to 0.88. ‒ by Monica Jaramillo
Disclosure: The research was supported by grants from the NIH/National Institute of Arthritis and Musculoskeletal and Skin Diseases: K24AR057827, T32AR055885.