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Top 7 most highly read articles of June
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Much of the news offered by Healio.com/Rheumatology in June was related to sessions presented at the European League Against Rheumatism Annual European Congress of Rheumatology, which took place from June 10-13 in Rome.
Psoriatic arthritis (PsA) was a topic that interested our readers, with coverage including research findings and a rejection from the National Institute for Heath and Care Excellence (NICE) of Otezla (apremilast, Celgene) for covered treatment of PsA. Other topics of interest included systemic sclerosis, myositis and fibromyalgia.
Psoriatic arthritis onset may be linked to trauma in patients with psoriasis
Research presented at the European League Against Rheumatism (EULAR) Annual European Congress of Rheumatology showed physical trauma may be associated with the development of psoriatic arthritis in patients with psoriasis.
A cohort study of 15,416 patients with psoriasis who were exposed to physical trauma were matched with 55,230 unexposed control patients without psoriasis from the Health Improvement Network (THIN) in the U.K. between 1993 and 2013. Read more.
Actemra gains FDA breakthrough status for systemic sclerosis, phase 2 data presented at EULAR
Actemra (tocilizumab, Genentech) has been granted breakthrough therapy designation by the FDA for the treatment of systemic sclerosis, and researchers presented data from a phase two study of tocilizumab in systemic sclerosis at the EULAR Annual European Congress of Rheumatology. Read more.
Methotrexate, cyclosporine not helpful to patients with myositis, poor response to glucocorticoids
Neither methotrexate nor cyclosporine improved symptoms in patients with dermatomyositis or polymyositis who did not respond fully to treatment with glucocorticoids, according to recently published research. Read more.
Study: About one-fourth of patients with FM had precipitating trauma, infection
Of patients with fibromyalgia, about one-fourth reported a precipitating event such as an infection or a physical or emotional trauma, according to recently published study findings.
Researchers retrospectively studied 978 patients with fibromyalgia (FM) seen by the authors as part of the fibromyalgia treatment program at the Mayo Clinic. Read more.
Fibromyalgia pain may be linked to pro-inflammatory cytokines, oxidized LDL levels
Certain pro-inflammatory cytokines and oxidized low-density lipoprotein may be associated with fibromyalgia pain, according to research presented at the EULAR Annual European Congress of Rheumatology. Read more.
NICE rejects Otezla for psoriatic arthritis coverage
After issuing guidance on the use of a number of biologic therapies for rheumatoid arthritis, the National Institute for Heath and Care Excellence (NICE) has turned down Otezla for coverage under the health care system in the U.K. for psoriatic arthritis, citing concerns about cost-effectiveness, according to documents published by the organization. Read more.
Residual disease activity lingers in patients with SLE
Active disease was common among patients with systemic lupus erythematosus, with 35% displaying active disease symptoms after a mean of 11 years, according to research from Christine A. Peschken MD, MSc, FRCPC, and colleagues presented at the Canadian Rheumatology Association Annual Meeting. Read more.