Alzheimer’s Disease/Dementia News

A customized speech transcription model logged roughly 30% fewer errors compared with manual or automated methods and may be a more effective tool in assessing verbal Alzheimer’s disease-related impairment.

Individuals with mild cognitive impairment performed faster on functional skills assessments and logged fewer dropouts when undergoing concurrent burst cognitive training, according to a poster from CTAD.

Participation in memory-based digital cognitive testing and blood-based biomarker assays for Alzheimer’s-related pathology was linked to successful enrollment into clinical trials for disease-modifying treatment, according to research.

The FDA has granted orphan drug designation to an investigational oral therapeutic for the treatment of Huntington’s disease, according to the manufacturer.

For individuals exposed to athletic-related head contact, glial fibrillary acidic protein may help identify those who are at risk for progressive regional brain atrophy and cognitive decline, per data from Alzheimer’s Research & Therapy.

In a diverse cohort of Hispanic/Latino individuals, longer sleep duration was associated with lower total brain and gray matter volume, according to research published in Alzheimer’s & Dementia.

Older adults with high levels or low levels of HDL had a small increased risk for dementia compared with those with average levels, researchers reported in Neurology.

PHILADELPHIA — The short-term effects of postmenopausal hormone therapies on the vascular system and the brain may differ from long-term effects and could be influenced by HT formulation and administration route, according to a speaker.

Adults diagnosed with HF before age 65 years were 67% more likely to be diagnosed with dementia during 12 years of follow-up compared with adults diagnosed at age 75 years or older, suggesting careful neurocognitive monitoring is needed.

PHILADELPHIA — A machine learning model was better able to predict preclinical Alzheimer’s disease from participant biomarkers as well as driving data from a year-long study, according to a speaker.