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November 20, 2023
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Kinematic, mechanical alignment had similar outcomes, radiographic failure after TKA

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Key takeaways:

  • Results showed no differences in patient-reported outcomes between the kinematic alignment and mechanical alignment groups.
  • Revision and reoperation were also not significantly different between the two groups.

GRAPEVINE, Texas — Results presented here showed no differences in functional outcomes or radiographic failure between kinematic alignment or mechanical alignment for total knee arthroplasty at 10-year follow-up.

John P. Gibbons, FRCS, and colleagues randomly assigned 99 patients undergoing TKA to receive either mechanical alignment (n=50) with computer navigation or kinematic alignment (n=49) with patient-specific cutting blocks. Researchers assessed patient-reported outcome measures, including Knee Society Score, Oxford Knee Score, Forgotten Joint Score and EuroQol-5D, as well as radiographs for signs of aseptic loosening. Researchers also determined survivorship free from reoperation and revision with Kaplan-Meier analysis.

Knee infection
Results showed no differences in patient-reported outcomes between the kinematic alignment and mechanical alignment TKA. Image: Adobe Stock

Among 39 patients in the kinematic group and 43 patients in the mechanical group available for follow-up at 10 years, Gibbons said the groups had no significant differences regarding patient-reported outcome measures.

John P. Gibbons
John P. Gibbons

“With regard to revision for any cause, we had four in the kinematic [group] and two in the mechanical [group], with revision being the addition or removal of any components,” Gibbons said during his presentation at the American Association of Hip and Knee Surgeons Annual Meeting. “This is the revision-free survival curve for both groups showing no significant difference.”

According to Gibbons, seven patients in the kinematic group had nine reoperations for any cause and five patients in the mechanical group had six reoperations for any cause. He added the survivorship curve for reoperation showed no significant difference between the two groups.

“With regard to the radiological analysis up to 5 and 10 years, we analyzed the X-rays in accordance to the technique described by Meneghini et al. and, again, looking at static and progressive lines and radiolucent lines, there was no significant difference between the kinematic and mechanical group,” Gibbons said.