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November 05, 2023
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Chronic anticoagulation may increase complications after revision THA

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Key takeaways:

  • Patients on chronic anticoagulation had an increased risk for complications at 90-days postoperatively.
  • Patients on chronic anticoagulation also had a 14% increased risk for rerevision at 2-years.

GRAPEVINE, Texas — Results presented here showed patients on chronic anticoagulation undergoing revision total hip arthroplasty had an increased risk for 90-day and 2-year complications.

“These patients need closer monitoring, to be counseled on their increased risk and we should not be scared to engage with out internal medicine colleagues to help with the management of these patients in the perioperative and postoperative period,” Rahul K. Goel, MD, said in his presentation at the American Association of Hip and Knee Surgeons Annual Meeting.

OT1123Goel_AAHKS_Graphic_01
Data were derived from Goel RK, et al. Paper 7. Presented at: American Association of Hip and Knee Surgeons Annual Meeting; Nov. 2-5, 2023; Grapevine, Texas.

Goel and colleagues retrospectively collected baseline comorbidity and demographic data among 10,000 patients who underwent revision THA between 2014 to 2019. Researchers categorized patients based on whether they were on chronic anticoagulation or not, and performed multivariate logistic regression models to identify the odds of developing postoperative complications between the two groups.

Rahul K. Goel
Rahul K. Goel

Goel said 20% of patients included in the study were on chronic anticoagulation.

“These patients were older, had more medical comorbidities and were more likely to be undergoing aseptic revision,” Goel said.

Patients on chronic anticoagulation had an increased risk for developing periprosthetic joint infection, surgical site infection and mechanical prosthetic complications at 90-days, according to Goel. He said patients on chronic anticoagulation had an increased risk for developing PJI at 2 years, as well as a 14% increased risk for rerevision.

“Looking at patients who were undergoing revision for septic reasons vs. aseptic reasons, we found both groups were at increased risk for developing PJI and the need for rerevision at 2 years,” Goel said.