VIDEO: Rodeo discusses human umbilical vein endothelial cells in rotator cuff repair
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WASHINGTON — At the American Academy of Orthopaedic Surgeons Next Generation of Biologics Symposium, Scott Rodeo, MD, FAAOS, spoke about a clinical study that used gene-modified human umbilical vein endothelial cells in rotator cuff repair.
The symposium was presented in collaboration with the Biologic Association.
“Our goal was could we leverage those intrinsic cells rather than necessarily relying on putting in exogenous cells, like cells from bone marrow or adipose tissue,” Rodeo said.
He said the phase 1 results showed that the cells were safe with no significant immune reaction seen against the cells. Additionally, the patient-reported outcome measures demonstrated standard improvements in function, strength and motion, and imaging demonstrated satisfactory healing, Rodeo said.
“The goal now is to use this data now to design a phase 2 study,” Rodeo said.
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