VIDEO: Speaker discusses new concepts, techniques for treatment of bone marrow lesions
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Key takeaways:
- Bone marrow lesions can decrease local progenitor cells, reducing the ability to heal.
- Types of bone marrow lesions include those that affect the bone, cause a cartilage defect and occur with osteoarthritis.
NEW ORLEANS — In this video, Bert R. Mandelbaum, MD, discusses new concepts, techniques and technologies for treatment of bone marrow lesions.
By understanding the pathogenesis of bone marrow lesions, Mandelbaum noted he and his colleagues categorized three types of bone marrow lesions. The first type of bone marrow lesion affects the bone.
“From a therapeutic approach, we’ve learned that core decompression, utilizing bone marrow aspirate concentration that brings in stems cells and other progenitor cells, allows us to revitalize the bone,” Mandelbaum told Healio.
The second type of bone marrow lesion causes a cartilage defect, according to Mandelbaum. He noted a core decompression and resurfacing procedure, like osteochondral allograft, is needed for treatment of type 2 bone marrow lesions.
“Bone marrow lesions number three are those lesions that occur concurrent to significant progressive Kellgren-Lawrence 1 to 3 osteoarthritis,” Mandelbaum said. “In those situations, which are also high pressure, a core decompression and, in certain cases, using bone marrow aspirate concentration demineralized matrix may have a significant effect to decrease pain, increase function and improve the patient outcome.”
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Mandelbaum BR. Treating the subchondral bone: Drilling, injection, calcium phosphate, BMAC and more. Presented at: Biologic Association Annual Summit; May 6-7,2023; New Orleans.
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