Recurrent mobile spine chondroma yielded high rate of complications
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CHICAGO — Results presented at the North American Spine Society Annual Meeting showed patients with recurrent mobile spine chondromas had a high rate of complications with or without surgical management.
Of 30 patients with recurrent mobile spine chondroma between 1995 and 2019, Joshua Kolz, MD, MS, and colleagues found 21 patients underwent revision resection and nine patients underwent nonoperative management. Kolz 76% of patients had positive margins at their index operation and 81% of patients undergoing revision resection had a positive margin. He added 67% of patients received chemotherapy or radiation therapy.
“Overall survival was 73% at 2 years, 39% at 5 years and 0% at 10 years,” Kolz said in his presentation. “There was no difference in overall survival based on anatomic location. There was no difference in overall survival when comparing surgical resection to those who underwent nonoperative management.”
Kolz patients had a local recurrence-free survival of 38% at 2 years and 11% at 5 years, with positive margins associated with local recurrence. He added patients had a metastatic-free survival of 77% at 2 years and 62% at 5 years.
“Those undergoing nonoperative management had a higher rate of metastases at 56% compared to 19% in those undergoing operative management,” Kolz said.
Complications occurred in 70% of patients, according to Kolz. He the most common complications for patients undergoing nonoperative treatment included neurologic decline followed by chronic painhe most common complications for patients undergoing operative management included medical complications followed by neurologic decline. Kolz said patients undergoing nonoperative management trended toward more neurologic decline compared with patients undergoing operative management.
“In those undergoing operative management, the reoperation rate was 52%,” Kolz said. “There were 19 total reoperations. These were most commonly done for recurrence and wound complications.”
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Kolz J, et al. Paper 60. Presented at: North American Spine Society Annual Meeting; Oct. 12-15, 2022; Chicago.
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