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January 11, 2022
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Speaker: Address underlying pathology to treat thoracic outlet syndrome

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WAIKOLOA, Hawaii — Treatment of neurogenic, venous or arterial thoracic outlet syndrome should be addressed at the underlying pathology to avoid consequences and frustration for patients and physicians, according to a presenter.

Perspective from John E. (Jed) Kuhn, MD, MS

“The thing about thoracic outlet syndrome – it’s tricky. It’s a challenging diagnosis. It’s not a specific test. It’s a clinical diagnosis,” Christopher S. Ahmad, MD, said in his presentation at Orthopedics Today Hawaii. “It’s frustrating to the patient, and it’s frustrating to the doctor,” he added.

The first step in diagnosing thoracic outlet syndrome is to rule out other pathologies, according to Ahmad. Humeral stress reaction, biceps tendinitis, cervical radiculopathy and nerve compression should all be ruled out, he said.

Christopher S. Ahmad
Christopher S. Ahmad

Similar to carpal tunnel syndrome, thoracic outlet syndrome is a compression problem, which can lead to vague symptoms depending on whether the pathology is neurogenic, vascular or arterial, Ahmad said.

Neurogenic thoracic outlet symptoms, such as numbness and paresthesia, are usually caused by compression of the brachial plexus by the cervical ribs, ligamentous bands or scalene muscles, Ahmad added. Failure of nonoperative treatment, such as rest, stretching, muscle relaxants and NSAIDs, should lead to referral to a vascular surgeon, he said.

Venous thoracic outlet syndrome is “not a hard diagnosis,” but it requires immediate attention, according to Ahmad. It is often caused by repetitive motion which leads to subclavian vein compression and the formation of a thrombus. These symptoms include swelling, cyanotic discoloration, heaviness and fatigue, he said. Nonsurgical treatment options are anticoagulants, thrombolysis and balloon angioplasty, while surgical options include axillary-subclavian vein decompression, rib resection and muscle removal.

Ahmad also outlined arterial thoracic outlet syndrome, in which symptoms include finger ischemia, numbness, tingling or discoloration. Treatment for this diagnosis can include anticoagulation, decompression or interposition bypass graft reconstruction, he said.

“You have to be ready to diagnose [thoracic outlet syndrome]. There is [a] consequence if you miss it, and the treatment is really at the underlying pathology,” Ahmad concluded.