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January 05, 2022
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Age among risk factors identified for postoperative VTE in pediatric orthopedic patients

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Preoperative blood transfusion, arthrotomy, femur fracture and patients aged 16 to 18 years are risk factors for venous thromboembolism among pediatric orthopedic surgical patients, results showed.

Researchers used the National Surgical Quality Improvement Program Pediatric database to retrospectively analyze data on 81,490 pediatric patients (mean age of 9.7 years) who underwent orthopedic surgery from 2012 to 2017. According to the study, patient demographics, comorbidities, and perioperative and postoperative outcomes were compared between the 60 patients (0.07%) who developed a postoperative venous thromboembolism (VTE) and those patients who did not.

After performing multivariate regression analysis, researchers determined patients aged 16 to 18 years, those with an American Society of Anesthesiologists class of III or greater and those who had a preoperative blood transfusion, arthrotomy or femur fracture were at increased risk for a postoperative VTE. Additionally, postoperative complications, reoperation and readmission were also identified as risk factors for VTE in this population.

“Although VTE is an uncommon complication among pediatric patients, it carries a high risk of morbidity and mortality,” the researchers wrote in the study. “These results can be used to identify pediatric patients undergoing orthopedic surgery who might benefit from prophylactic anticoagulation, with the aim of reducing morbidity and optimizing postoperative outcomes.”